Diffusion tensor tractography in cerebral small vessel disease: correlation with cognitive function

Hypertension and cerebral diffusion tensor imaging in small vessel disease.

BACKGROUND AND PURPOSE Hypertension is a risk factor for cerebral small vessel disease, which includes white matter lesions (WML) and lacunar infarcts. These lesions are frequently observed on MRI scans of elderly people and play a role in cognitive decline. Preferably, one would like to evaluate the effect of hypertension before fluid-attenuated inversion recovery visible macrostructural lesio...

Diffusion tensor imaging and gait in elderly persons with cerebral small vessel disease.

BACKGROUND AND PURPOSE Although cerebral small vessel disease, including white matter lesions (WML) and lacunar infarcts, is associated with gait disturbances, not all individuals with small vessel disease have these disturbances. Identical-appearing WML on MRI could reflect different degrees of microstructural integrity. Moreover, conventional MRI does not assess the integrity of normal-appear...

Fiber Tractography and Diffusion Tensor Imaging in Children with Agenesis and Dysgenesis of Corpus Callosum: A Clinico-Radiological Correlation

Background Corpus callosum is the largest commissure in human brain. It consists of tightly packed white matter tracts connecting the two cerebral hemispheres.  In this study we aimed to evaluate role of fiber tractography (FT), and diffusion tensor imaging (DTI) in ped...

Diffusion tensor imaging and cognition in cerebral small vessel disease: the RUN DMC study.

BACKGROUND Cerebral small vessel disease (SVD) is very common in elderly and related to cognition, although this relation is weak. This might be because the underlying pathology of white matter lesions (WML) is diverse and cannot be properly appreciated with conventional FLAIR MRI. In addition, conventional MRI is not sensitive to early loss of microstructural integrity of the normal appearing ...

White Matter Microstructural Damage on Diffusion Tensor Imaging in Cerebral Small Vessel Disease: Clinical Consequences.